| 1/1/2021, Fri | International New Year Day |
- Note
- A paid public holiday.
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| 1/7/2021, Thu | Victory over Genocide Day |
- Note
- A paid public holiday. Commemorates the 7 January 1979 fall of Democratic Kampuchea (Khmer Rouge) with Vietnamese assistance.
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| 3/8/2021, Mon | International Women's Day |
- Note
- A paid public holiday.
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| 4/13/2021, Tue | Khmer New Year Day 1 |
- Note
- A paid public holiday (Chaul Chnam Thmey / Maha Sangkranta).
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| 4/14/2021, Wed | Khmer New Year Day 2 |
- Note
- A paid public holiday (Vireak Vanabat).
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| 4/15/2021, Thu | Khmer New Year Day 3 |
- Note
- A paid public holiday (Vireak Loeng Sak).
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| 5/1/2021, Sat | International Labor Day |
- Note
- A paid public holiday.
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| 5/14/2021, Fri | King Norodom Sihamoni's Birthday |
- Note
- A paid public holiday (King Norodom Sihamoni's Birthday, b. 14 May 1953).
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| 5/26/2021, Wed | Visak Bochea |
- Note
- A paid public holiday. Celebrates the birth, enlightenment, and passing into Nirvana (death) of Gautama Buddha.
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| 5/30/2021, Sun | Royal Ploughing Ceremony |
- Note
- A paid public holiday (Preah Reach Pithi Chrat Preah Neangkol).
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| 6/18/2021, Fri | Queen Mother Norodom Monineath Sihanouk's Birthday |
- Note
- A paid public holiday (Queen Mother Norodom Monineath Sihanouk's Birthday, b. 18 June 1936).
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| 9/24/2021, Fri | Constitutional Day |
- Note
- A paid public holiday. Commemorates the promulgation of the 1993 Cambodian Constitution on 24 September.
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| 10/18/2021, Mon | Pchum Ben Day 1 |
- Note
- A paid public holiday. Ancestor Veneration Festival for departed relatives.
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| 10/19/2021, Tue | Pchum Ben Day 2 (Ben Thom) |
- Note
- A paid public holiday (Ben Thom / the "great Ben").
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| 10/20/2021, Wed | Pchum Ben Day 3 |
- Note
- A paid public holiday (Pchum Ben Day 3).
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| 10/21/2021, Thu | Commemoration of the Late King Father Norodom Sihanouk |
- Note
- A paid public holiday. Commemorates the death of the Late King Father Norodom Sihanouk on 15 October 2012.
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| 10/29/2021, Fri | Coronation Day of King Norodom Sihamoni |
- Note
- A paid public holiday. Commemorates the coronation of King Norodom Sihamoni on 29 October 2004.
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| 11/9/2021, Tue | National Independence Day |
- Note
- A paid public holiday. Commemorates Cambodia's independence from France on 9 November 1953.
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| 11/18/2021, Thu | Water Festival Day 1 |
- Note
- A paid public holiday (Bon Om Touk).
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| 11/19/2021, Fri | Water Festival Day 2 |
- Note
- A paid public holiday (Bon Om Touk).
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| 11/20/2021, Sat | Water Festival Day 3 |
- Note
- A paid public holiday (Bon Om Touk).
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| 12/29/2021, Wed | Peace Day in Cambodia |
- Note
- A paid public holiday.
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